Glutathione S-transferase (GSTs) theta 2 (GSTT2) is amember of a superfamily of proteins that catalyze the conjugationof reduced glutathione to a variety of electrophilic andhydrophobic compounds. Human GSTs can be divided into five mainclasses: Alpha, Mu, Pi, Theta, and Zeta. The theta class membersGSTT1 and GSTT2 share 55% amino acid sequence identity and both arethought to have an important role in human carcinogenesis. Thetheta genes have a similar structure, being composed of five exonswith identical exon/intron boundaries.
Titration of the GSTT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 113-141 from the human protein was used as the immunogen for this GSTT2 antibody.
Aliquot the GSTT2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
