
The protein encoded by this gene is involved in thesynthesis of the unbranched glycosaminoglycan hyaluronan, orhyaluronic acid, which is a major constituent of the extracellularmatrix. This gene is a member of the NODC/HAS gene family. Comparedto the proteins encoded by other members of this gene family, thisprotein appears to be more of a regulator of hyaluronan synthesis.Alternative splicing results in multiple transcript variants.
Titration of the HAS3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 137-164 from the human protein was used as the immunogen for this HAS3 antibody.
Aliquot the HAS3 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.