Heme oxygenase 2, also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. Heme oxygenases cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

The stated application concentrations are suggested starting amounts.Titration of the Heme Oxygenase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Human partial recombinant protein (AA 2-316) was used as the immunogen for this Heme Oxygenase 2 antibody.

After reconstitution, the Heme Oxygenase 2 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.