First described in relation to heat shock, HSPs are now known to be produced in response to additional stressful conditions including cold and UV light, as well as during wound healing. Heat shock protein 60 (HSP60) is responsible for protein transportation from the cytoplasm to the mitochondrial matrix and the subsequent refolding of the transported proteins.HSP60 also functions as a molecular chaperone, or chaperonin, assisting linear amino acid chains to fold into their three-dimensional structure.

Provided assay concentrations are suggestions only, HSP60 antibody titration may be required for optimal results.

A recombinant protein fragment from human HSP60 was used as the immunogen for this antibody.

Aliquot the HSP60 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.

Chaperonin 60-KD (CPN60), GROEL, HLD4, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, Hsp60s1, Spastic paraplegia 13 (SPG13), HSP60 antibody