Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This HSP90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 57-89 amino acids from the N-terminal region of human HSP90AA1.

Aliquot the HSP90 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.