Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Titration of the Integrin beta 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 759-785 from the human protein was used as the immunogen for this Integrin beta 1 antibody.

Aliquot the Integrin beta 1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.