The product of this gene belongs to the integrin alphachain family. Integrins are heterodimeric integral membraneproteins composed of an alpha chain and a beta chain. This geneencodes the integrin alpha 5 chain. Alpha chain 5 undergoespost-translational cleavage in the extracellular domain to yielddisulfide-linked light and heavy chains that join with beta 1 toform a fibronectin receptor. In addition to adhesion, integrins areknown to participate in cell-surface mediated signalling. [providedby RefSeq].

Titration of the Integrin alpha 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 796-822 from the human protein was used as the immunogen for this Integrin alpha 5 antibody.

Aliquot the Integrin alpha 5 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.