LMO2 encodes a cysteine-rich, two LIM-domain protein thatis required for yolk sac erythropoiesis. The LMO2 protein has acentral and crucial role in hematopoietic development and is highlyconserved. The LMO2 transcription start site is locatedapproximately 25 kb downstream from the 11p13 T-cell translocationcluster (11p13 ttc), where a number T-cell acute lymphoblasticleukemia-specific translocations occur. Alternative splicingresults in multiple transcript variants encoding differentisoforms.

Titration of the LMO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 1-30 from the human protein was used as the immunogen for this LMO2 antibody.

Aliquot the LMO2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.