
NR5A2 (nuclear receptor subfamily 5, group A, member 2) also known as liver receptor homolog-1 (LRH-1) is a protein that in humans is encoded by the NR5A2 gene. This protein is a member of the nuclear receptor family of intracellulartranscription factors. It plays a critical role in the regulation of development, cholesterol transport, bile acid homeostasis andsteroidogenesis. LRH-1 is important for maintaining pluripotence of stem cells during embryonic development. Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.
The stated application concentrations are suggested starting amounts.Titration of the LRH-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 44-237) was used as the immunogen for this NR5A2 / LRH-1 antibody.
After reconstitution, the LRH-1 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.