Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (aM/b2) molecule, also known as macrophage-1 antigen (Mac-1) or cluster of differentiation molecule 11b (CD11b). It is mapped to 16p11.2. ITGAM/CD11b has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What"s more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

Optimal dilution of the mouse CD11b antibody should be determined by the researcher.

A mouse recombinant protein corresponding to amino acids E260-T360 was used as the immunogen for the mouse CD11b antibody.

After reconstitution, the mouse CD11b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.