Myeloperoxidase (MPO) is a heme protein synthesized duringmyeloid differentiation that constitutes the major component ofneutrophil azurophilic granules. Produced as a single chainprecursor, myeloperoxidase is subsequently cleaved into a light andheavy chain.The mature myeloperoxidase is a tetramer composed of2 light chains and 2 heavy chains. This enzyme produces hypohalousacids central to the microbicidal activity of netrophils. [providedby RefSeq].
Titration of the MPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 548-575 from the human protein was used as the immunogen for this MPO antibody.
Aliquot the MPO antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
