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当前位置: 首页 > 产品中心 > monoclonal_antibody > NSJ Bio/Neutrophil elastase Antibody (F41911)/0.4 ml/F41911-0.4ML
商品详细NSJ Bio/Neutrophil elastase Antibody (F41911)/0.4 ml/F41911-0.4ML
NSJ Bio/Neutrophil elastase Antibody (F41911)/0.4 ml/F41911-0.4ML
NSJ Bio/Neutrophil elastase Antibody (F41911)/0.4 ml/F41911-0.4ML
商品编号: F41911-0.4ML
品牌: NSJBioreagents
市场价: ¥7580.00
美元价: 6064.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description

Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteins. Theproduct of this gene hydrolyzes proteins within specializedneutrophil lysosomes, called azurophil granules, as well asproteins of the extracellular matrix following the protein"srelease from activated neutrophils. The enzyme may play a role indegenerative and inflammatory diseases by its proteolysis ofcollagen-IV and elastin of the extracellular matrix. This proteindegrades the outer membrane protein A (OmpA) of E. coli as well asthe virulence factors of such bacteria as Shigella, Salmonella andYersinia. Mutations in this gene are associated with cyclicneutropenia and severe congenital neutropenia (SCN). This gene isclustered with other serine protease gene family members,azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3genes are expressed coordinately and their protein products arepackaged together into azurophil granules during neutrophildifferentiation.

Application Notes

Titration of the Neutrophil elastase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 13-39 from the human protein was used as the immunogen for this Neutrophil elastase antibody.

Storage

Aliquot the Neutrophil elastase antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.

品牌介绍
NSJ Bioreagents已有20多年的历史。 NSJ Bio提供领先的、广泛使用的单克隆抗体以及单克隆和多克隆抗体的所有领域的研究,包括肿瘤,肿瘤生物标志物,细胞凋亡,免疫学,细胞生物学和转录因子。产品提供多种规格,以更好地适应研究人员的测试需求和预算限制。   链接:http://www.nsjbio.com/ 温馨提示:不可用于临床治疗。 风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。