NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. [UniProt]

The stated application concentrations are suggested starting points. Titration of the NFKB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A human recombinant protein was used as the immunogen for this NFKB1 antibody.

Store the NFKB1 antibody at -20oC.