SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.

Titration of the p-SOX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This p-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS83 of human SOX2.

Aliquot the p-SOX2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.