This gene encodes Platelet-derived growth factor receptor-like protein, a protein with significant sequence similarity to the ligand binding domain of platelet-derived growthfactor receptor beta. Mutations in this gene, or deletion of achromosomal segment containing this gene, are associated withsporadic hepatocellular carcinomas, colorectal cancers, andnon-small cell lung cancers. This suggests this gene product mayfunction as a tumor suppressor.
Titration of the PDGFRL antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 16-44 from the human protein was used as the immunogen for this PDGFRL antibody.
Aliquot the PDGFRL antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
