Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP.Phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and is proposed to participate in the angiogenic process as a disulfide reductase.Mutations in PGK1 may be associated with hemolytic anemia.
Titration of the PGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 305-334 from the human protein was used as the immunogen for this PGK1 antibody.
Aliquot the PGK1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
