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当前位置: 首页 > 产品中心 > Functional_antibody > NSJ Bio/Rab8 Antibody (R31404)/100 ug/R31404
商品详细NSJ Bio/Rab8 Antibody (R31404)/100 ug/R31404
NSJ Bio/Rab8 Antibody (R31404)/100 ug/R31404
NSJ Bio/Rab8 Antibody (R31404)/100 ug/R31404
商品编号: R31404
品牌: NSJBioreagents
市场价: ¥8380.00
美元价: 6704.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description

Ras-related protein Rab8 is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. Rab8 regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of Rab8 into the cilium during assembly of this organelle. It has been shown to interact with Optineurin and MAP4K2.

Application Notes

The stated application concentrations are suggested starting amounts.Titration of the Rab8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Rab8A (KAKMDKKLEGNSPQ) was used as the immunogen for this Rab8 antibody (100% homologous in human, mouse and rat).

Storage

After reconstitution, the Rab8 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.

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