S100A4/FSP1 (Fibroblast specific protein 1) belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including p53, p63, non-muscle myosin IIA, a6b4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.

The optimal dilution of the S100A4 antibody for each application should be determined by the researcher.

Human recombinant S100A4 protein was used as the immunogen for this S100A4 antibody.

Store the S100A4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).