The intronless gene for SOX2 encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
Titration of the SOX-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 89-119 from the human protein was used as the immunogen for this SOX-2 antibody.
Aliquot the SOX-2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
