This gene is a member of the stromal interaction molecule(STIM) family and likely arose, along with related family memberSTIM1, from a common ancestral gene. The encoded protein functionsto regulate calcium concentrations in the cytosol and endoplasmicreticulum, and is involved in the activation of plasma membraneOrai Ca(2+) entry channels. This gene initiates translation from anon-AUG (UUG) start site. A signal peptide is cleaved from theresulting protein. Multiple transcript variants result fromalternative splicing.
Titration of the STIM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 98-127 from the human protein was used as the immunogen for this STIM2 antibody.
Aliquot the STIM2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
