The nuclear gene TAT encodes the mitochondrial protein Tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked.

Optimal dilution of the TAT antibody should be determined by the researcher.

Amino acids 169-208 (FSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEK-human) were used as the immunogen for the TAT antibody.

After reconstitution, the TAT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.