This gene is a member of a conserved family of genes thatshare a common DNA-binding domain, the T-box. T-box genes encodetranscription factors involved in the regulation of developmentalprocesses. A similar protein has been disrupted in mice and shownto be critical for early cortical development, and causes loss ofprojection neurons in the olfactory bulbs and olfactory cortex. TheC-terminal region this similar protein was found to be necessaryand sufficient for association with the guanylate kinase domain ofcalcium/calmodulin-dependent serine protein kinase. [provided byRefSeq].

Titration of the TBR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 52-80 from the human protein was used as the immunogen for this TBR1 antibody.

Aliquot the TBR1 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.