TRAPPC2 is thought to be part ofa large multi-subunit complex involved in the targeting and fusionof endoplasmic reticulum-to-Golgi transport vesicles with theiracceptor compartment. In addition, the encoded protein can bindc-myc promoter-binding protein 1 and block its transcriptionalrepression capability. Mutations in this gene are a cause ofspondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogeneof this gene is located on chromosome 19, and other pseudogenes arefound on chromosomes 8 and Y.
Titration of the TRAPPC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 11-39 from the human protein was used as the immunogen for this TRAPPC2 antibody.
Aliquot the TRAPPC2 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
