TRIL or TLR4 interactor with leucine rich repeats, is a protein encoded by the human KIAA0644 gene.TRIL protein sequence is highly conserved across species.It is expressed in a number of tissues with highest expression in brain, ovary, small intestine and spleen.TRIL is an accessory molecule that interacts with TLR3 and endosomal TLR4, enhancing their interaction with their ligands, poly(I:C) and LPS, and increasing the production of type I interferons in the innate immune response.

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

A recombinant protein fragment from the C-terminal region of human TRIL was used as the immunogen for this antibody.

Aliquot the antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.

TLR4 interactor with leucine rich repeats