Microtubules of the eukaryotic cytoskeleton performessential and diverse functions and are composed of a heterodimerof alpha and beta tubulin. The genes encoding these microtubuleconstituents are part of the tubulin superfamily, which is composedof six distinct families. Genes from the alpha, beta and gammatubulin families are found in all eukaryotes. The alpha and betatubulins represent the major components of microtubules, whilegamma tubulin plays a critical role in the nucleation ofmicrotubule assembly. There are multiple alpha and beta tubulingenes and they are highly conserved among and between species. Thisgene encodes an alpha tubulin that is a highly conserved homolog ofa rat testis-specific alpha tubulin.

Titration of the TUBA4A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

A portion of amino acids 417-446 from the human protein was used as the immunogen for this TUBA4A antibody.

Aliquot the TUBA4A antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.