The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Titration of the UBC9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This UBC9 antibody was raised using purified GST-UBC9 fusion protein.

Aliquot the UBC9 antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.