The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Titration of the VEGFC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

This monoclonal antibody was produced from mice immunized with peptides from human VEGFC.

Aliquot the VEGFC antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.